QuickView for map kinase kinase 4;jsessionid=1D824B8B58CC9B5F126B0BD4F69A6D06;jsessionid=3A1930DB298319E4860CC25A37B4A6AF;jsessionid=CBF591F2CFF33F8DCBC9863F585B49E0;jsessionid=11A6099739A62854BE2F2159F6B76E62;jsessionid=54424FDE803FC4D6B094D374308A2AFE (gene)
- Gene Symbol:
- PBS2
Saccharomyces cerevisiae - Full name:
- MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress
- Synonyms:
- HOG4, PBS2, SFS4, SSK4, YJL128C
- Genomic Location:
- Chr X: 178094-180100
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
structural molecule activity | kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | signaling adaptor activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | molecular adaptor activity | MAP-kinase scaffold activity | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | MAP kinase kinase activity | transferase activity, transferring phosphorus-containing groups | protein-containing complex scaffold activity | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | protein serine/threonine/tyrosine kinase activity | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
actin filament-based process | hyperosmotic response | intracellular signal transduction | peptidyl-amino acid modification | actin cytoskeleton organization | establishment of localization | regulation of MAP kinase activity | activation of MAPK activity involved in osmosensory signaling pathway | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | response to antibiotic | intracellular transport | cellular process | localization | protein transport | positive regulation of protein kinase activity | macromolecule localization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | regulation of cellular process | regulation of metabolic process | protein import into nucleus | positive regulation of cellular protein metabolic process | cellular component organization | MAPK cascade | response to stimulus | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | intracellular protein transport | protein localization to nucleus | protein serine/threonine kinase activity | supramolecular fiber organization | cellular localization | response to temperature stimulus | positive regulation of protein serine/threonine kinase activity | protein modification process | macromolecule modification | activation of protein kinase activity | osmosensory signaling pathway | stress-activated protein kinase signaling cascade | signaling adaptor activity | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | phosphorus metabolic process | actin filament organization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | organic substance transport | cellular response to stress | cellular response to heat | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | peptide transport | positive regulation of intracellular signal transduction | protein localization to organelle | import into nucleus | response to osmotic stress | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | protein import | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | MAP-kinase scaffold activity | regulation of protein phosphorylation | cellular hyperosmotic response | protein tyrosine kinase activity | positive regulation of molecular function | activation of MAPK activity | protein metabolic process | positive regulation of protein modification process | regulation of kinase activity | MAP kinase kinase activity | cellular response to osmotic stress | regulation of intracellular signal transduction | establishment of protein localization to organelle | metabolic process | cellular protein localization | amide transport | protein kinase activity | organic substance metabolic process | nuclear transport | positive regulation of kinase activity | response to heat | regulation of phosphate metabolic process | cytoskeleton organization | establishment of protein localization | positive regulation of MAPK cascade | regulation of cell communication | signaling | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | cellular macromolecule localization | positive regulation of MAP kinase activity | protein serine/threonine/tyrosine kinase activity | nucleocytoplasmic transport | kinase activity | organelle organization | cellular protein modification process | positive regulation of metabolic process | cellular metabolic process | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
cellular bud neck | cytoplasmic stress granule | cell | ribonucleoprotein granule | cytoplasm | intracellular organelle | protein-containing complex | cellular bud | ribonucleoprotein complex | site of polarized growth | organelle | cytoplasmic ribonucleoprotein granule | cellular bud tip | intracellular
